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Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae cephalosporin-resistant strain H041 acylated by ceftriaxone

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae cephalosporin-resistant strain H041 acylated by ceftriaxone Descriptor: CEFOTAXIME, C3' cleaved, open, ... Authors: Singh, A, Davies, C. Deposit date: 2019-12-18 Release date: 2020-04-15 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Mutations in Neisseria gonorrhoeae penicillin-binding protein 2 associated with extended-spectrum cephalosporin resistance create an energetic barrier against acylation via restriction of protein dynamics J.Biol.Chem., 2020

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2019-12-18
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