Pogz deficiency leads to abnormal behavior, transcription dysregulation and impaired cerebellar physiology

As part of characterizing the novel pogz deficiency mouse model, we performed RNA-Seq from cerebellum and hippocampus of adult mice to discover Pogz targets and changes in gene expression that might explain the phenotypes we see in those mice Cerebellar and hippocampal mRNA profiles of control (WT), pogz+/- and pogz-/- mice, both males and females, in triplicates, using Illumina NextSeq 500