Replication Data for: Intestinal Disturbances Associated with Mortality of Children with Complicated Severe Malnutrition

This is a replication dataset for the manuscript titled: "Replication Data for: Intestinal Disturbances Associated with Mortality of Children with Complicated Severe Malnutrition." This is data is from a case-control study nested within the F75 intervention trial. By comparing the fecal metabolomic profiles and enteropathy markers between cases (children who died, n=68) and controls (children who were discharged alive, n=68), this study aimed to understand the association between intestinal disturbances wnad mortality among children with severe malnutrition admitted to hospitals in Kenya and Malawi. Targeted fecal metabolomics were performed using nuclear magnetic resonance spectroscopy. A total 68 metabolites were targeted. Four enteropathy markers, myeloperoxidase, calprotectin, alpha-1-antitrypsin, and intestinal fatty acid binding protein were quantified by ELISA. Lyophilization was used to determine water content of fecal samples.