Gene expression analysis in canine Vogt-Koyanagi-Harada/uveodermatologic syndrome and vitiligo. Gene expression analysis in canine Vogt-Koyanagi-Harada/uveodermatologic syndrome and vitiligo

We performed a comparative immunology case study of client-owned dogs to determine if immune and skin gene expression profiles in spontaneous canine VKH and vitiligo mirror those observed in human autoimmune pigmentary diseases. Overall design: Gene expression was analyzed using 160 custom Nanostring probes to analyze 2 canines with VKH and 1 canine with vitiligo compared to 5 healthy controls (leg margin excisions).