Over-represented TFBSs and other novel motifs in U-CGI fragments.

We use matrix entry of TRANSFAC which could be mapped uniquely to denote TFBS in the first column, and similarly in the tables hereinafter. The second column indicates whether the TFs corresponding to the over-represented TFBSs have been reported to express in human brain. The two numbers in the 3th�C8th columns are the p-values in the two-step hypothesis test in the corresponding fragment (we use p1 and p2 to represent the upper and lower value respectively). Only the TFBS with p1 less than Bonferroni-adjusted p-value cutoff 0.01 and p2 less than 0.01 is regarded as a significantly enriched TFBS in the fragment, and is marked in bold. Here we regard TFBSs or novel motifs that are simultaneously significant in more than 3 U-CGI fragments as over-represented TFBSs or over-represented novel motifs in U-CGIs.*Y: The TF corresponding to the TFBS has been reported to express in human brain; N: The TF corresponding to the TFBS has not been reported to express in human brain; -: No information about the TF corresponding to the motif.Similarly in the tables hereinafter.