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Supplemental Tables and appendices for JAAD article
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2019-03-28
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Transcriptomic changes in fibroblasts in the course of photoaging
Skin, similar to most other organs, undergoes detremental changes during life time (intrinsic or chronological aging). Unique for skin, however, is its direct environmental exposure, particularly UV i
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Appendix
Appendix to the original article called : "Skin photoaging around the site of occurrence of primary melanoma as a clinical predictive biomarker of response to PD-1 inhibitors: A retrospective study."
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Whole genome expression data from pre-auricular and post-auricular skin tissues
Photoaging is cumulative damage that is caused by chronic, repeated solar radiation exposure to skin. Its molecular mechanisms are poorly understood at the level of global gene expression.This study s
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Chip-chip from human epidermis with H3ac. Chip-chip from human epidermis with H3ac
The UV radiation induced epigenetic changes play an important role in photoaging, but experimental evidence of histone modification to support this perspective has been scarce. Analyse the histone H3
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Solar simulated ultraviolet radiation induces histone 3 methylation changes in the gene promoters of matrix metalloproteinases 1 and 3 in primary human dermal fibroblasts [II]. Homo sapiens
Skin damage from solar ultraviolet radiation (UVR) accumulates in the dermal extracellular matrix (ECM) and contributes to photoaging. Following UVR exposure, matrix metalloproteinases (MMPs) are secr
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