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Heterozygous SNORA31 mutations in patients with herpes simplex encephalitis

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https://www.ncbi.nlm.nih.gov/sra/SRP114432
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Pseudo-seq was used to measure differences in the extent of pseudouridine (?) modification in rRNA from human cell lines with heterozygous, and homozygous disruptions of SNORA31. Overall design: CMC treatment of RNA followed by next generation sequencing was used to measure the extent of pseudouridylation at mapped human rRNA ? sites. CMC: carbodiimide N-cyclohexyl-N'-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate
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2020-01-14
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