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ATAC-seq of NCI-H358 cells treated with KRAS G12C inhibitor sotorasib

NIAID Data Ecosystem2026-05-02 收录

肿瘤耐药机制

表观基因组药物响应

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE266309 数据链接链接失效反馈

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资源简介：

ATAC-seq of sotorasib-resistant NCI-H358 cells treated with sotorasib NCI-H358 cells were treated with DMSO or 1uM sotorasib for 72 hour

应用场景：

创建时间：

2025-07-16

肿瘤耐药机制

靶向药物组合

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miRNA表达谱

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Reversing Melanoma Cross-Resistance to BRAF and MEK Inhibitors by Co-Targeting the AKT/mTOR Pathway

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信号通路靶向治疗

BackgroundThe sustained clinical activity of the BRAF inhibitor vemurafenib (PLX4032/RG7204) in patients with BRAFV600 mutant melanoma is limited primarily by the development of acquired resistance le

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Gene expression profiling in carmustine-resistant melanoma A2058 cells

肿瘤耐药机制

基因表达谱分析

Analysis of gene expression and compare the significant changed genes with associated phenotypes. Total RNA extracted from parental or carmustine-resistant A2058 cells.

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AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition. Homo sapiens

肿瘤耐药机制

组合治疗

EGFR-mut NSCLC lines show differential suceptibility to inhibition of tankyrase in the presence of EGFR inhibitors Overall design: NSCLC cells were treated in quadruplicate with gefitinib, AZ1366 (tan

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ATAC-seq of NCI-H358 cells treated with KRAS G12C inhibitor sotorasib

资源简介：

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