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Protective activity of mRNA vaccines

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DataCite Commons2024-09-20 更新2025-04-16 收录
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https://www.immport.org/shared/study/SDY2741
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Although mRNA vaccines encoding the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) prevent COVID-19, the emergence of new viral variants jeopardizes their efficacy. Here, we assessed the immunogenicity and protective activity of historical (mRNA-1273, designed for Wuhan-1 spike protein) or modified (mRNA-1273.351, designed for B.1.351 spike protein) Moderna mRNA vaccines in 129S2 and K18-hACE2 mice.
提供机构:
ImmPort
创建时间:
2024-09-20
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