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资源简介：
explore the underlying molecular mechanism of NCoR1-mediated HSCs homeostasis and function
应用场景：
创建时间：
2018-02-27
相关数据集
Epigenetic modifier Smchd1 maintains a normal pool of long-term repopulating hematopoietic stem cells in mice I
We have used a conditional mouse model to investigate the role of Smchd1 specifically in hematopoiesis. We found that Smchd1-deleted mice have an altered hematopoietic stem and progenitor cell (HSPC)
NIAID Data Ecosystem100
STAT1 is essential for hematopoietic stem cell function and maintains a MHC IIhi stem cell subset that resists myeloablation and neoplastic expansion. STAT1 is essential for hematopoietic stem cell function and maintains a MHC IIhi stem cell subset that resists myeloablation and neoplastic expansion
Adult hematopoietic stem cells (HSCs) are predominantly quiescent and can be activated in response to acute stress such as infection or cytotoxic insults. STAT1 is a pivotal mediator of interferon (IF
NIAID Data Ecosystem50
The E3 ubiquitin ligase DDB1 controls homeostasis of hematopoietic stem and progenitor cells
The E3 ubiquitin ligase DDB1 controls homeostasis of hematopoietic stem and progenitor cells
ChEBI2015-07-10 更新30
Cell cyclin kinase inhibitor Cdkn2c regulates B cell homeostasis and function in the NZM2410-derived murine lupus susceptibility locus Sle2c1. Mus musculus
Sle2c1 is an NZM2410-derived lupus susceptibility locus that induces an expansion of the B1a cell compartment. B1a cells have a repertoire enriched for autoreactivity, and an expansion of this B cell
NIAID Data Ecosystem70
Non-catalytic functions of Tet2 are essential to regulate hematopoietic stem and progenitor cell homeostasis. Non-catalytic functions of Tet2 are essential to regulate hematopoietic stem and progenitor cell homeostasis
To identify genes that are influenced by the catalytic and non-catalytic functions of Tet2 in hematopoietic stem and progenitor cells (HSPCs), we analyzed the gene expression profiles of Tet2 catalyti
NIAID Data Ecosystem50
