Isolated Blood Immune Cell Transcriptomics in COPD

We observed separation of COPD patients from control smokers by CD4+ T cell transcriptomics. In contrast to CD4+ T cells, there were no transcript differences in whole blood, CD8+ T cells or CD14+ monocytes. We examined transcripts of CD4+ T cells (n=79), CD8+ T cells (n=75) and CD14+ T cells (n=75) isolated from the whole blood of subjects. The control group were smokers without COPD. We examined differences between COPD and controls.