Novel culture conditions facilitating the induction of naïve pluripotency in human embryonic stem cells

ChEBI2015-06-29 更新2026-07-12 收录

干细胞重编程

多能性调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-57318 数据链接链接失效反馈

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资源简介：

Novel culture conditions facilitating the induction of naïve pluripotency in human embryonic stem cells

创建时间：

2015-06-29

BMP4 Resets Primed to Naive Pluripotency by Reprogramming Chromatin Accessibility [RNA-Seq]

干细胞重编程

染色质可及性分析

Mouse naive and primed pluripotent stem cells, ESC and EpiSC, represent two distinct stages of pluripotency. Here we report that BMP4 drives primed to naive transition or PNT by reprogramming chromati

NIAID Data Ecosystem70

Analysis of Differential Proteomes of Induced Pluripotent Stem Cells by Protein-Based Reprogramming of Fibroblasts

干细胞重编程

蛋白质组学比较分析

The recent generation of induced pluripotent stem (iPS) cells represents a novel opportunity to complement embryonic stem (ES) cell-based approaches. iPS cells can be generated by viral transduction o

Figshare2016-02-23 更新50

Defining Essential Regulators of Naïve Human Pluripotent Cell Reprogramming. Defining Essential Regulators of Naïve Human Pluripotent Cell Reprogramming

干细胞重编程

CRISPRi功能基因组学

Defining how human pluripotent cell identity is controlled and in particular how naïve pluripotency is acquired during cell reprogramming is crucial for the future applications of pluripotent stem cel

NIAID Data Ecosystem30

Reprogramming of mouse somatic cells into pluripotent stem cells using a combination of small molecules

干细胞重编程

化学生物学

Somatic cells can be reprogrammed to generate induced pluripotent stem cells (iPSCs) by overexpression of four transcription factors, Oct4, Klf4, Sox2, and c-Myc. Bmi1 is responsible for conversion o

NIAID Data Ecosystem60

Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency [RNA-seq]. Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency [RNA-seq]

干细胞重编程

染色质可及性调控

Chemical induction of pluripotency (CIP) is an ideal way to reprogram cell fate, but remains poorly understood. Here we report the development of an efficient CIP protocol and the chromatin accessibil

NIAID Data Ecosystem40

Novel culture conditions facilitating the induction of naïve pluripotency in human embryonic stem cells

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