IRAK4 in complex with Compound 21
收藏Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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IRAK4 in complex with Compound 21 Descriptor: Interleukin-1 receptor-associated kinase 4, SULFATE ION, ~{N}4,~{N}4-dimethyl-~{N}1-[5-(oxan-4-yl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl]cyclohexane-1,4-diamine Authors: Ferguson, A.D. Deposit date: 2016-05-25 Release date: 2017-12-06 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse Large B-Cell Lymphoma. J. Med. Chem., 60, 2017
创建时间:
2016-05-25



