Full-resolution confocal microscopy and time-lapse imaging data supporting "In vivo CRISPRi-seq identifies essential pneumococcal vulnerabilities during meningitis"

This dataset contains full-resolution confocal microscopy z-stacks and time-lapse recordings associated with the study "In vivo CRISPRi-seq identifies essential pneumococcal vulnerabilities during meningitis". The microscopy data were generated using a zebrafish (Danio rerio) embryo model of Streptococcus pneumoniae meningitis. The images support the visualization of bacterial infection, host-pathogen interactions, and fluorescence-based analyses presented in the manuscript and its Supplementary Information. The dataset provides the underlying imaging data to support the interpretation, verification, and reproducibility of the microscopy experiments reported in the study. Associated manuscript: In vivo CRISPRi-seq identifies essential pneumococcal vulnerabilities during meningitis. Institution: University of Lausanne, Switzerland.