aArm A, irinotecan followed by oxaliplatin-based regimens; arm B, oxaliplatin followed by irinotecan-based regimens. SD: standard deviation; CCI: Charlson comorbidity index; CVD: cardiovascular diseas
The cell of origin in glioblastoma is not formally proven but generally accepted to be a neural stem cell or glial precursor cell. In addition, there is also limited knowledge about the functional con