To assess the m 6 A methylome in the anterior capsule of the lens of high myopia patients. MeRIP-seq and RNA-seq were performed to identify differences in the m 6 A methylomes and ge
Introduction: Severe central visual field defects are frequently observed in eyes with high myopia. We report the clinical features of two patients each with a central visual field defect; they had hi
Introduction: Crystalline lens is the major dioptric component and varies with refractive status. In this study, we aim to evaluate the changes of dimensions and functions of crystalline lens in high
Aims: A previous genome-wide association study of high myopia identified five genome-wide loci for ocular axial length (C3orf26, ZC3H11B, RSPO1, GJD2, and ZNRF3). The aim of our study wa
A total of 201 potential variants were identified in 27 families: 139 ones were well cosegregated with the disease in 15 families. Sixty-two variants were not cosegregated
