Although most patients with multiple myeloma respond to treatment initially, therapy resistance develops almost invariably and only a subset of patients show durable responses to immunomodulatory (IMi

NIAID Data Ecosystem40

Additional file 4 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG

细胞信号通路

CRISPR-Cas9基因编辑

: Table S2. Detail of genes expression of clustering Nanog, pEPS and embryos.

Figshare2020-02-19 更新20

Murine Gammaherpesvirus M2 Protein Induction of IRF4 via the NFAT Pathway Leads to IL-10 Expression in B Cells

疱疹病毒基因调控

细胞信号通路

Reactivation of the gammaherpesviruses Epstein-Barr virus (EBV), Kaposi's sarcoma-associated herpesvirus (KSHV) and murine gammaherpesvirus 68 (MHV68) from latently infected B cells has been linked to

Figshare2016-01-18 更新50

Retinoic Acid Therapy Resistance Progresses from Unilineage to Bilineage in HL-60 Leukemic Blasts

白血病化疗耐药

细胞信号通路

Emergent resistance can be progressive and driven by global signaling aberrations. All-trans retinoic acid (RA) is the standard therapeutic agent for acute promyelocytic leukemia, but 10–20% of patien

Figshare2016-01-15 更新20

Effects of physiological and synthetic IAP antagonism on c-IAP dependent signaling

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