succinylCoA + GDP + Pi <=> succinate + CoASH + GTP

Mitochondrial succinyl-CoA synthetase catalyzes the reversible reaction of succinylCoA, GDP, and orthophosphate to form succinate, CoASH, and GTP. The enzyme is a heterodimer consisting of an alpha chain and a beta chain that determines whether the reaction involves adenine nucleotides or guanine nucleotides (as here). The biochemical properties of the chicken enzyme have been studied in detail (Hamilton and Ottaway 1981) but the genes encoding its component proteins have not been cloned. The molecular properties of these proteins are inferred from those of their pigeon homologues (Johnson et al. 1998).

线粒体琥珀酰辅酶A合酶催化琥珀酰辅酶A、鸟苷二磷酸和正磷酸的可逆反应，生成琥珀酸、辅酶A-SH和三磷酸鸟苷。此酶为异源二聚体，由α链和β链组成，决定反应是否涉及腺苷核苷或鸟苷核苷（如本例所示）。鸡酶的生化特性已被详细研究（Hamilton和Ottaway，1981年），但其组成蛋白的编码基因尚未被克隆。这些蛋白的分子特性是通过其鸽类同源物的特性推断得出的（Johnson等人，1998年）。