HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY

HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY Descriptor: HIV-1 PROTEASE, [4R-(4ALPHA,5ALPHA,6BETA,7BETA)]-3,3'-[[TETRAHYDRO-5,6-DIHYDROXY-2-OXO-4,7-BIS(PHENYLMETHYL)-1H-1,3-DIAZEPINE-1,3(2H)-D IYL] BIS(METHYLENE)]BIS[N-2-THIAZOLYLBENZAMIDE] Authors: Ala, P, Chang, C.-H. Deposit date: 1997-04-25 Release date: 1997-10-15 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV. J.Med.Chem., 40, 1997