Hyperactive RAS/MAPK introduces cancer-specific mitotic vulnerabilities
收藏NIAID Data Ecosystem2026-03-14 收录
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资源简介：
We performed tanscriptional profiling of ARPE19 and four isogenic transformed cells lines in which Ras or two downstream pathways, MAPK or PI3K/mTOR, were up-regulated. The purpose of this study is to understand how Ras signaling impacts kinetochore function. mRNA-seq transcriptome profilng performed in triplicate on each of the five cell lines.
创建时间：
2022-12-25
