Effect of SARS-CoV-2 infection and BNT162b2 vaccination on the mRNA expression of genes associated with angiogenesis

COVID-19 is multisystemic with varying degrees of severity. Unfortunately, despite intensive research, the molecular changes caused by Sars-CoV-2 still remain unclear. Mechanisms affected by virus infection include endothelial dysfunction and angiogenesis. Similarly, the vaccines developed so far affect the process of angiogenesis, contributing to the development of undesirable effects on the part of the cardiovascular system. Therefore, we aimed to detect the impact of the SARS-CoV-2 infection and Pfizer Comirnaty vaccine on the molecular aspect of angiogenesis.