CRYSTAL STRUCTURE OF BTK IN COMPLEX WITH COVALENT INHIBITOR
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CRYSTAL STRUCTURE OF BTK IN COMPLEX WITH COVALENT INHIBITOR Descriptor: 6-[(3S)-3-(acryloylamino)pyrrolidin-1-yl]-2-{[4-(tert-butylcarbamoyl)phenyl]amino}pyridine-3-carboxamide, DIMETHYL SULFOXIDE, Tyrosine-protein kinase BTK Authors: GARDBERG, A. Deposit date: 2018-05-23 Release date: 2018-09-05 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hit. Bioorg. Med. Chem. Lett., 28, 2018
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2018-05-23
