Background: The role of human epidermal growth factor receptor 2 (HER2) in metaplastic breast cancer (MBC) patients remains unclear. The present study aimed to evaluate the effect of HER2 status on MB
Several transgenic mice models solidly support the hypothesis that HER2 (ERBB2) overexpression or mutation promotes tumorigenesis. Recently, a HER2 splice variant lacking exon-16 (Δ16HER2) has been de
Abbreviations: HER2, human epidermal growth factor receptor 2; IHC, immunohistochemistry; ISH, in-situ hybridization; SISH, silver in-situ hybridization; N, number.*HER2 positivity was defined as HER2