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Crystal structure of human BCL6 BTB domain in complex with compound 1

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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Crystal structure of human BCL6 BTB domain in complex with compound 1 Descriptor: 1,2-ETHANEDIOL, 5-[[2-[(3~{S},5~{R})-4,4-bis(fluoranyl)-3,5-dimethyl-piperidin-1-yl]-5-chloranyl-pyrimidin-4-yl]amino]-1-methyl-3-(3-methyl-3-oxidanyl-butyl)benzimidazol-2-one, B-cell lymphoma 6 protein Authors: Rodrigues, M.J, Le Bihan, Y.-V, van Montfort, R.L.M. Deposit date: 2019-12-11 Release date: 2020-04-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: AchievingIn VivoTarget Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders. J.Med.Chem., 63, 2020

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2019-12-11
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