Transcription profiling by array of mouse tissues from different mouse strains to investigate the effects of copy number variation on gene expression

Copy number variation (CNV) of DNA segments has recently been identified as a major source of genetic diversity, but a more comprehensive understanding of the extent and phenotypic effect of this type of variation is only beginning to emerge. In this study we generated genome-wide expression data from 6 mouse tissues to investigate how CNVs influence gene expression. Keywords: genetic background, gene expression profiling C57BL/6J, DBA2/J, AKR/J, A/J and C3HeB/FeJ were purchased from The Jackson Laboratory and 129S2 from Charles River, France. Six tissues were dissected from three males of 11-14 weeks of age, for each strain.