Inhibitor of MDM2-p53 Interaction
收藏Protein Data Bank Japan2024-05-15 更新2026-03-21 收录
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Inhibitor of MDM2-p53 Interaction Descriptor: (3~{R})-4-chloranyl-3-(4-chlorophenyl)-3-[[1-(hydroxymethyl)cyclopropyl]methoxy]-2-[(4-nitrophenyl)methyl]isoindol-1-one, E3 ubiquitin-protein ligase Mdm2 Authors: Williams, P.A. Deposit date: 2021-01-13 Release date: 2021-04-07 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction. J.Med.Chem., 64, 2021
创建时间：
2021-01-13
