Expression data from human esophageal cancer cells. Expression data from human esophageal cancer cells

When esophageal cancer cells are exposed to a certain dose of radiation, a series of biological process changes, including DNA damage, DNA repair, apoptosis, cell cycle, repopulation, mitotic disasters, etc. These changes may determine the radiotherapy sensitivity to esophageal cancer, as well as recurrence and metastasis after radiotherapy. To clarify the changes in gene expression in esophageal cancer after radiotherapy, we used gene expression microarrays to screen for significant up-regulation and down-regulation of genes and to analyze associations with these biological processes. Overall design: Test groups(T) and Control groups(C) were selected for RNA extraction and hybridization on Affymetrix Clariom S Assay. Test groups(T): 2 flasks of cells were given a radiation dose of 18 Gy at 6 frequencies. Control groups(C): 2 flasks of cells were cultured normally.