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Inactivation of the nuclear interacting SET domain protein 1 (NSD1) impairs GATA1-regulated erythroid differentiation and causes erythroleukemia. NSD1 Add-back experiment. ChIPSeq for Gata1, H3K27ac and H3K36me3.

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE136808
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资源简介:
In vitro differentiation of Nsd1-/- erythroblasts with retroviral expression of wildtype Nsd1, or a catalytically-inactive Nsd1N1918Q SET-domain Add-back experiment with cultured Nsd1-/- erythroblasts rescued with either retroviral expression of wildtype Nsd1, or a catalytically-inactive Nsd1N1918Q SET-domain
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2021-11-17
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