Effects of systemic injection of a non-selective dopamine D<sub>2</sub>-like receptor antagonist, haloperidol, on the number, duration, and relative power of HVSs, and HVS-related coherence of the M1–GP pair.
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A: number of HVSs. B: duration of HVSs. C: representative averaged relative power spectral density curve of the M1 cortex (ECoG), and of GP LFP recorded from the saline-treated rats (black lines) and raclopride-treated rats (red or blue lines). D: relative power of both the M1 cortex and GP LFP in the frequency bands associated with HVS oscillations. E: averaged coherence curves of the M1–GP pair in the saline-treated rats (black lines) and haloperidol-treated rats (red or blue lines). F: coherence values relating to the HVSs. SAL, saline; HAL 1.0, haloperidol 1.0 mg/kg; HAL 3.0, haloperidol 3.0 mg/kg; HVSs, high-voltage spindles; M1, primary motor cortex; GP, globus pallidus. *P<0.05 and **P<0.01 vs. saline. #Significant difference between HAL 1.0 and HAL 3.0.
