Identification of Kdm4a, b and c target genes in MLL-AF9 transformed mouse GMPs (L-GMP)

ChEBI2016-06-02 更新2026-07-12 收录

白血病表观遗传学

组蛋白去甲基化酶靶基因鉴定

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资源简介：

Identification of Kdm4a, b and c target genes in MLL-AF9 transformed mouse GMPs (L-GMP)

创建时间：

2016-06-02

BET inhibition releases the Mediator complex from specific cis elements in acute myeloid leukemia cells (ChIP-Seq II)

白血病表观遗传学

染色质免疫沉淀测序

Genome occupancy profiling by high throughput sequencing ChIP-seq of Brd4 with or without Doxycycline treatment to induce Med12 or Med23 shRNAs in MLL-AF9 transformed acute myeloid leukemia cells (RN2

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Effect of DNMT3A R882H mutation or WT on gene expression in hematopoietic stem/progenitor cells with NRAS G12D co-transduction (Microarray). Mus musculus

细胞恶性转化

白血病表观遗传学

DNA Methyltransferase 3A (DNMT3A) is frequently mutated in various hematopoietic malignancies; however, the underlying oncogenic mechanisms remain elusive. Here, we report that DNMT3A mutational ‘hots

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Unraveling MLL1-fusion Leukemia: Epigenetic Revelations from an iPS Cell Point Mutation

白血病表观遗传学

干细胞基因编辑

Human iPS cells (WT ASE9203 cells) were obtained from Applied Stem Cell (ASC), and CRISPR-Cas9-mediated gene editing was completed by ASC using their proprietary CRISPR-Cas9 protocol to introduce the

NIAID Data Ecosystem60

RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (DNase-Seq)

白血病表观遗传学

染色质可及性分析

RUNX1 is a frequent target of translocations in acute myeloid leukemia whereby its DNA binding domain fuses to different epigenetic regulators. To assess how different RUNX1 fusion proteins interact w

NIAID Data Ecosystem90

Additional file 7 of Loss of H3K27 methylation identifies poor outcomes in adult-onset acute leukemia

白血病表观遗传学

基因突变关联分析

Additional file 7: Table S3. Pairwise associations between driver mutations presented by Pearson's Correlation Coefficient (cor) and p-value (p).

NIAID Data Ecosystem70