Supplementary Material for: Noncutaneous Visceral Kaposi Sarcoma of the Stomach and Liver: A Case Report

Introduction: Kaposi sarcoma (KS) is an angioproliferative neoplasm caused by human herpes virus-8 (HHV8), most commonly affecting immunocompromised individuals, particularly those with HIV/AIDS. While KS typically presents with violaceous cutaneous lesions, visceral involvement, especially in the gastrointestinal and hepatic systems, is rare and often asymptomatic.
Case Presentation: We describe an uncommon presentation of AIDS-related KS involving the liver, stomach, and lungs in a 25-year-old male with poorly controlled HIV. Despite the absence of cutaneous manifestations, KS was diagnosed with a high index of suspicion, and appropriate treatment was initiated with antiretroviral therapy (ART) along with plans to initiate chemotherapy in the outpatient setting.
Conclusion: This case highlights the importance of considering visceral KS in HIV/AIDS patients even in the absence of skin lesions, as early diagnosis and intervention can improve patient outcomes.