IGF2 DMR methylation in the child and independent factors of the mother and the child.

Linear Mixed Model analysis. Data are presented in percentage (standard error) of mean change in relative methylation. For independent quantitative parameters the change in relative methylation is given per SD-change in that parameter. The p-value of the significant association of periconceptional folic acid use and IGF2 DMR methylation was additionally adjusted for maternal education. The p-value for the significant association between maternal SAM and IGF2 DMR methylation was also adjusted for maternal education and the SAM concentration of the child. The p-value for the significant association between IGF2 DMR methylation and birth weight was additionally adjusted for periconceptional folic acid use and gestational age at delivery.