Crystal Structure of the Bace complex with AXQ093, a macrocyclic inhibitor
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Crystal Structure of the Bace complex with AXQ093, a macrocyclic inhibitor Descriptor: Beta-secretase 1, {(E)-(3R,6S,9R)-3-[(1S,3R)-3-((S)-1 -BUTYLCARBAMOYL-2-METHYL-PROPYLCARB AMOYL)-1-HYDROXY-BUTYL]-6-METHYL-5, 8-DIOXO-1,11-DITHIA-4,7-DIAZA-CYCLO PENTADEC-13-EN-9-YL}-CARBAMIC ACID TERT-BUTYL ESTER Authors: Rondeau, J.-M. Deposit date: 2005-11-21 Release date: 2006-09-05 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). J.Med.Chem., 49, 2006
创建时间：
2005-11-21
