CDK9-Cyclin-T1 complex bound by compound 24
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CDK9-Cyclin-T1 complex bound by compound 24 Descriptor: (1~{S},3~{R})-3-acetamido-~{N}-[5-chloranyl-4-(5,5-dimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl]cyclohexane-1-carboxamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cyclin-T1, ... Authors: Ferguson, A, Collie, G.W. Deposit date: 2020-05-22 Release date: 2020-12-23 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.37 Å) Cite: Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies. J.Med.Chem., 63, 2020
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2020-05-22
