The liver is the central organ for carbohydrate metabolism to maintain the blood glucose concentration within a normal range. Glucose breakdown or synthesis in the liver is tightly regulated by insuli

DataCite Commons2022-01-12 更新60

Analysis of C. elegans DAF-16 phosphorylation in different genetic backgrounds.

胰岛素信号通路

蛋白质磷酸化

C. elegans DAF-16/FOXO phosphorylation in different genetic backgrounds was analyzed by mass spectrometry of affinity purified HA-tagged DAF-16. Genetic backgrounds studied include par-1 hypomorphic m

NIAID Data Ecosystem40

Feedback Inhibition of CREB Signaling Promotes Beta Cell Dysfunction in Insulin Resistance.

细胞功能障碍

胰岛素信号通路

Although persistent elevations in circulating glucose concentrations promote compensatory increases in pancreatic islet mass, unremitting insulin resistance causes a deterioration in beta cell functio

NIAID Data Ecosystem70

Additional file 3 of In-depth phosphoproteomic profiling of the insulin signaling response in heart tissue and cardiomyocytes unveils canonical and specialized regulation

磷酸化蛋白质组学

胰岛素信号通路

Supplementary Table S3. List of phosphopeptides quantified upon insulin stimulation in isolated cardiomyocytes. Results of functional enrichment analyses.

DataCite Commons2024-08-17 更新60

Diabetes-related pathways and their respective codes.

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