Plasma protein-profiling to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma (LA-NPC). Plasma protein-profiling to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma (LA-NPC)

Plasma protein expression patterns can be used as prognostic biomarkers in various types of cancer. We aimed to identify a protein-based signature for distant metastatic risk assessment in patients with locoregionally advanced nasopharyngeal carcinoma (LA-NPC). Overall design: Using Raybiotech Quantibody Human Kiloplex Proteomics Array (QAH-CAA-X00), we detected 1000 plasma protein expression between 8 LA-NPC plasma samples with distant metastasis after radical treatment and 8 LA-NPC plasma samples without distant metastasis after radical treatment to identify distant metastasis-related proteins.