Additional file 5: Table S5. of Gene expression and adaptive noncoding changes during human evolution

Functional correlations between differential expression overall and noncoding adaptation. All MSigDB collections we considered are listed except for C2:CP:BioCarta, in which no gene set contained at least 50 genes analyzed in a previous study of adaptive noncoding changes. # sets is the number of gene sets we considered in the collection. rr is the rank correlation between rank-biserial correlations for enrichment with differential expression and rank-biserial correlations for enrichment with noncoding adaptation. p(rr) is the one-tailed p-value of rr via permutation test with 10,000 permutations; collections are ordered by increasing p(rr), which reflects rr, # sets, and patterns of overlap among gene sets in the collection. (XLSX 63 kb)