DCTD_Aginome-XMU Round 1 submitted models

Team Aginome-XMU submitted models to DREAM Challenge Tumor Deconvolution

The Challenge consisted of a “coarse-grained” sub-Challenge, during which participants predicted levels of eight major immune and stromal cell populations [including B cells, CD4+ and CD8+ T cells, NK cells, neutrophils, cells within the monocytic lineage (monocytes/macrophages/dendritic cells), endothelial cells, and fibroblasts].

The Challenge also consisted of a “fine-grained” sub-Challenge, during which participants further dissected major populations into 14 minor sub-populations according to their functional orientation (e.g., naive B cells, memory B cells, naive CD4 T cells, memory CD4 T cells, naive.CD8 T cells, memory CD8 T cells, regulatory T cells, monocytes, macrophages, myeloid dendritic cells, NK cells, neutrophils, endothelial cells, and fibroblasts).

Aginome-XMU 团队向 DREAM 挑战赛提交了肿瘤去卷积模型。该挑战赛包括一个“粗粒度”子挑战，在此期间，参与者预测了八种主要免疫和基质细胞群体（包括B细胞、CD4+和CD8+T细胞、自然杀伤细胞、中性粒细胞、单核细胞谱系细胞（单核细胞/巨噬细胞/树突状细胞）、内皮细胞和成纤维细胞）的水平。此外，挑战赛还包括一个“细粒度”子挑战，在此期间，参与者根据其功能取向进一步将主要群体细分为14个亚群体（例如，原始B细胞、记忆B细胞、原始CD4 T细胞、记忆CD4 T细胞、原始CD8 T细胞、记忆CD8 T细胞、调节性T细胞、单核细胞、巨噬细胞、髓树突状细胞、自然杀伤细胞、中性粒细胞、内皮细胞和成纤维细胞）。