five

Crystal structure of SET7/9 in complex with cyproheptadine

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal structure of SET7/9 in complex with cyproheptadine Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(dibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-1-methyl-piperidine, Histone-lysine N-methyltransferase SETD7, ... Authors: Niwa, H, Handa, N, Takemoto, Y, Ito, A, Tomabechi, Y, Umehara, T, Shirouzu, M, Yoshida, M, Yokoyama, S. Deposit date: 2015-08-20 Release date: 2016-04-27 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.005 Å) Cite: Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription J.Med.Chem., 59, 2016
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2015-08-20
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