T. cruzi topoisomerase II alpha bound to dsDNA and the covalent inhibitor CT1
收藏Protein Data Bank Japan2024-11-06 更新2026-06-30 收录
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T. cruzi topoisomerase II alpha bound to dsDNA and the covalent inhibitor CT1 Descriptor: 2-{3-[(Z)-iminomethyl]-1H-1,2,4-triazol-1-yl}-1-{(3M)-3-[2-(trifluoromethyl)phenyl]-6H-pyrrolo[3,4-b]pyridin-6-yl}ethan-1-one, DNA (28-MER), DNA topoisomerase 2 Authors: Schenk, A, Deniston, C, Noeske, J. Deposit date: 2023-03-01 Release date: 2023-07-12 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (2.94 Å) Cite: Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science, 380, 2023
创建时间：
2023-03-01
