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Genome-wide DNA methylation seq data and RNA seq data in three paired HCC and normal tissue samples

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1103867
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Hepatocellular carcinoma (HCC) has a high mortality rate, and the mechanisms of tumorigenesis and progression are not well understood. However, inactivated oncogenes may play a key role. DNA methylation is a key regulatory mechanism for oncogene inactivation in HCC. In this study, genomic DNA (gDNA) was extracted from 3 pairs of HCC and normal tissue samples to study methylation-associated tumor suppressors in HCC to identify potential biomarkers and therapeutic targets.
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2024-04-23
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