Genome-wide DNA methylation seq data and RNA seq data in three paired HCC and normal tissue samples

Hepatocellular carcinoma (HCC) has a high mortality rate, and the mechanisms of tumorigenesis and progression are not well understood. However, inactivated oncogenes may play a key role. DNA methylation is a key regulatory mechanism for oncogene inactivation in HCC. In this study, genomic DNA (gDNA) was extracted from 3 pairs of HCC and normal tissue samples to study methylation-associated tumor suppressors in HCC to identify potential biomarkers and therapeutic targets.