PINK1 and PRKN, which cause Parkinson disease when mutated, form a quality control mitophagy pathway that is well-characterized in cultured cells. The extent to which the PINK1-PRKN pathway contribute
Currently, there is limited understanding about hormonal regulation of mitochondrial turnover. Thyroid hormone (T 3 ) increases oxidative phosphorylation (OXPHOS), which generates reactive ox
