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The IL-4/STAT6/PPARγ signaling axis is driving the extension of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages

NIAID Data Ecosystem2026-03-13 收录

巨噬细胞调控

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数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110465 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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创建时间：

2021-12-10

组织特异性表观遗传学

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Estrogen has vascular protective effects in premenopausal women and in women under 60 receiving hormone replacement therapy. However, estrogen also increases risks of breast and uterine cancers and of

NIAID Data Ecosystem100

Analysis of estrogen-induced mRNA in endometrial cancer cells with forced expression of ER. Analysis of estrogen-induced mRNA in endometrial cancer cells with forced expression of ER

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子宫内膜癌转录组分析

We used the endometrial adenocarcinoma cell line in which the ERα cDNA gene was transfected and forcedly expressed ER. Then the factors induced by estrogen (Estradiol: E2) were measured by microarray.

NIAID Data Ecosystem50

Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.. Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.

乳腺癌分子机制

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Inhibitory crosstalk between estrogen receptor alpha (ER alpha ) and aryl hydrocarbon receptor (AHR) regulates 17-estradiol (E2)-dependent breast cancer cell signaling. ER alpha and AHR are transcript

NIAID Data Ecosystem40

AhR signalling in enteric neurons. AhR signalling in enteric neurons

肠道神经系统

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This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem60

Temporal transcriptional response from primary human chronic lymphocytic leukemia (CLL)-cells after B-cell receptor stimulation.

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慢性淋巴细胞白血病转录组

The B-cell receptor (BCR) signaling is crucial for the pathophysiology of most leukemias and lymphomas originated from mature B lymphocytes and has emerged as a new therapeutic target, especially for

NIAID Data Ecosystem40

The IL-4/STAT6/PPARγ signaling axis is driving the extension of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages

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