PQM-1 Governs Stress Resilience through DAF-16 and Dietary Cues in C. elegans

The goal of this study was to identify genes controlled by PQM-1 during heat stress conditions (35 degrees celsius) in young adult C. elegans, independent of DAF-16 and the Insulin-like-signaling pathway. Overall design: Gene expression profile of Day1 adult C. elegans at 20 degrees celsius and after exposure to 1 hour at 35 degrees celsius (Heat Shock) of a control strain (N2), a daf-16 (mu86) mutant (strain CF1038) and a pqm-1 (ok485) null mutant (strain RB711). Worms were collected after a 2 hour recovery period at 20 degree celsius. 3 biological replicates of each sample.