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Gene expression profile in Liver of 10mo old MANFHet mice

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Transcriptome analysis comparing livers of 10 month old MANFHet mice and WT littermates revealed the induction of genes associated with inflammation, apoptosis, collagen deposition, usually observed in association with liver damage, along with alterations in lipid metabolism. RNA was extracted and sequenced for 8 litermates, 4 animals/genotype

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