Characterization of an abiraterone ultra-responsive phenotype in castration-resistant prostate cancer patient-derived xenografts
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE85672
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资源简介：
To identify the molecular signature associated with abiraterone acetate (AA) response and mechanisms underlying AA resistance in castration-resistant prostate cancer patient-derived xenografts (PDXs). SCID mice bearing LuCaP 136CR, 77CR, 96CR, and 35CR PDXs were treated with AA. Tumors response were followed, and tumors were harvested 7 days post-treatment (D7) and at end of study (EOS) for gene expression profiling using the Affymetrix Human Genome U219 Array Plate platform. Four replicates per PDX, treatment, and timepoint were profiled.
创建时间：
2016-12-24
