Correction of FFPE artefacts in WGS data
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https://www.omicsdi.org/dataset/ega/EGAS00001005331
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The ability to precisely characterise mutational signatures from FFPE-derived DNA has tremendous translational potential. However, sequencing of DNA derived from FFPE material is known to be riddled with artefacts. To correct for this, we introduce FFPEsig, a computational algorithm to rectify the formalin-induced artefacts in the mutational profile.EGA study EGAS00001005331
创建时间:
2021-06-02



