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Synthesis of Reboxetine Intermediate and Carnitine Acetyltransferase Inhibitor via NBS-Induced Electrophilic Multicomponent Reaction

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NIAID Data Ecosystem2026-03-08 收录
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https://figshare.com/articles/dataset/Synthesis_of_Reboxetine_Intermediate_and_Carnitine_Acetyltransferase_Inhibitor_via_NBS_Induced_Electrophilic_Multicomponent_Reaction/2291218
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资源简介:
N-Bromosuccinimide-induced electrophilic multicomponent reaction has been applied to the synthesis of Reboxetine intermediate, a highly potent selective norepinephrine reuptake inhibitor. By simply changing the olefinic partner, the synthesis of a carnitine acetyltransferase inhibitor, which contains a 2,6,6-trisubstituted morpholine system, can be accomplished.
创建时间:
2014-05-16
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