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Extrathymic expression of Aire controls the induction of effective TH17 cell-mediated immune response to Candida albicans

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE203158
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To investigate the effect of Candida albicans on ILC3 cells and dendritic cells these subytpes were isolated by flow cytometry, in similar fashion candida specific T-cells were obtained and subjected to bulk mRNA sequencing mRNA profiling of conventional ILC3, MHCII+ ILC3, Aire+ ILC3 and DCs in homeostasis or stimulated by heat-killed Candida albicans. mRNA profilling of T-cells stimulated by Candida albicans, mRNA profiling of Aire-suficient or deficient Aire-expressing ILC3 cells stimulated by Candida albicans
创建时间:
2022-07-05
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